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Elbow Flexor Adaptations to Failure Versus Repetitions-in-Reserve Training: A Unilateral Within-Participant Study in Resistance-Trained Adults

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This study compared elbow flexor hypertrophy and maximal strength adaptations after eight weeks of resistance training performed either to momentary muscular failure or with 1–3 repetitions in reserve (RIR). Nineteen resistance-trained adults completed a unilateral within-participant protocol in which one arm trained to failure and the contralateral arm trained with 1–3 RIR. Participants trained twice weekly using the unilateral preacher curl exercise at 70–80% one-repetition maximum (1RM). Elbow flexor muscle thickness and 1RM strength were assessed before and after the intervention. Bayesian mixed-effects models estimated between-condition differences. Both protocols increased muscle thickness and 1RM strength. The estimated between-condition differences for muscle thickness were 0.032 cm (95% highest density interval [HDI]: −0.044 to 0.113) while the estimated difference in 1RM strength was 0.588 kg (85% HDI: −0.491 to 1.66), with both 95% HDIs spanning zero and including values favoring either protocol. Sex-specific analyses showed the same general patter of responses. Overall, resistance training performed with 1–3 RIR produces similar elbow flexor hypertrophy and maximal strength adaptations to training performed to momentary muscular failures under the loading and volume conditions examined.

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resistance training hypertrophy muscle thickness strength

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Vasconcelos, T., Alves, A. R., Refalo, M. C., Lucas, G. C., Vasconcelos, P. R., Paulo Brito, J., Casanova, F., Vilaça-Alves, J., & Oliveira, R. (2026). Elbow Flexor Adaptations to Failure Versus Repetitions-in-Reserve Training: A Unilateral Within-Participant Study in Resistance-Trained Adults. Muscles, 5(3), 61. https://doi.org/10.3390/muscles5030061

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