Publication
Phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: A cross-sectional exploratory pilot study
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Advisor(s)
Abstract(s)
The aim of the present cross-sectional exploratory pilot study was to analyze the ability of the
Phase Angle (PhA) to predict physical function, muscle strength and bone indicators, upon
adjusting for potential confounders [age, sex, lean mass, and body mass index (BMI)]. This study
included 56 physically independent older adults (age, 68.29 ± 3.01 years; BMI, 28.09 ± 4.37 kg/
m2
). A multi-frequency segmental bioelectrical impedance analysis was used to measure PhA at
50 KHz. Additionally, physical function was assessed through four functional capacity tests [30-
sec chair-stand; seated medicine ball throw (SMBT); timed up & go; and 6-min walking test (6
MWT)], muscle strength through the handgrip test (dominant side) and maximal isokinetic
strength of the dominant knee flexor and extensor. Moreover, bone indicators and body
composition were assessed through the dual energy X-ray absorptiometry.
PhA was significantly associated with SMBT (r = 0.375, effect size (ES) = moderate); 6 MWT (r
= 0.396, ES = moderate); 30-sec chair-stand (rho = 0.314, ES = moderate); knee extension (rho
= 0.566, ES = large) and flexion (r = 0.459, ES = moderate); handgrip (rho = 0.432, ES =
moderate); whole-body bone mineral content (BMC) (r = 0.316, ES = moderate); femoral neck
BMC (r = 0.469, ES = moderate); and femoral neck bone mineral density (BMD) (rho = 0.433, ES
= moderate). Additionally, the results of multiple regression analysis demonstrated that PhA is
significantly associated with SMBT (p < 0.001; R2 = 0.629), 6 MWT (p = 0.004; R2 = 0.214), knee
extension (p < 0.001; R2 = 0.697), knee flexion (p < 0.001; R2 = 0.355), handgrip test (p < 0.001;
R2 = 0.774), whole-body BMC (p < 0.001; R2 = 0.524), femoral neck BMC (p = 0.001; R2 =
0.249), and femoral neck BMD (p = 0.020; R2 = 0.153). The results of the preliminary analysis
suggested that PhA is linked to muscle strength and some factors related to physical function and
bone quality in community-dwelling older adults.
Description
Keywords
aging elderly bioelectrical impedance analysis bone mineral density functional capacity skeleton
Citation
Martins, A., Brito, J.,Batalha,N.,Oliveira, R., Parraca, J.M. & Fernandes, O. (2023). Phase angle as a key marker of muscular and bone quality in community-dwelling independent older adults: A cross-sectional exploratory pilot study. Heliyon, 9 (7).
Publisher
Cell Press