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Angiotensin-converting enzyme genotype affects skeletal muscle strength in elite athletes

2009Journal article Open access
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dc.contributor.authorCosta, Aldo
dc.contributor.authorSilva, António
dc.contributor.authorGarrido, Nuno
dc.contributor.authorLouro, Hugo
dc.contributor.authorMarinho, Daniel
dc.contributor.authorMarques, Mário
dc.contributor.authorBreitenfeld, Luisa
dc.date.accessioned2021-08-09T14:58:23Z
dc.date.available2021-08-09T14:58:23Z
dc.date.issued2009
dc.description.abstractPrevious studies have associated angiotensin-converting enzyme (ACE) D allele with variability in the skeletal muscle baseline strength, though conclusions have been inconsistent across investigations. The purpose of this study was to examine the possible association between ACE genotype and skeletal muscle baseline strength in elite male and female athletes involved in different event expertise. A group of 58 elite athletes, designated as Olympic candidates, were studied: 35 swimmers (19 males and 16 females, 18.8 ± 3.2 years) and 23 triathletes (15 males and 8 females, 18.7 ± 3.0 years). The athletes were classified as: short (≤ 200m) and middle (400m to 1500m) distance athletes, respectively. For each subject the grip strength in both hands was measure using an adjustable mechanical hand dynamometer. The maximum height in both squat jump (SJ) and counter movement jump (CMJ) were also assessed, using a trigonometric carpet (Ergojump Digitime 1000; Digitest, Jyvaskyla, Finland). DNA extraction was obtained with Chelex 100® and genotype determination by PCR-RFLP methods. Both males and females showed significantly higher right grip strength in D allele carriers compared to II homozygote’s. We found that allelic frequency differs significantly by event distance specialization in both genders (p < 0.05). In fact, sprinter D allele carriers showed the superior scores in nearly all strength measurements (p < 0.05), in both genders. Among endurance athletes, the results also demonstrated that female D allele carriers exhibited the higher performance right grip and CMJ scores (p < 0.05). In conclusion, the ACE D allele seems associated with skeletal muscle baseline strength in elite athletes, being easily identified in females.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCosta, A., Silva, A.J., Garrido, N., Louro, H., Marinho, D.A., Marques, M.C. & Breitenfeld, L. (2009) Angiotensin-Converting Enzyme Genotype Affects Skeletal Muscle Strength In Elite Athletes. Journal of Sports Science and Medicine (08), 410 - 418.pt_PT
dc.identifier.issn1303 - 2968
dc.identifier.urihttp://hdl.handle.net/10400.15/3571
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMedical Faculty of Uludag Universitypt_PT
dc.relation.publisherversionhttps://www.jssm.org/jssm-08-410.xml%3EFulltext#pt_PT
dc.subjectswimmingpt_PT
dc.subjecttriathlonpt_PT
dc.subjectgenetic polymorphismpt_PT
dc.subjectsport performancept_PT
dc.titleAngiotensin-converting enzyme genotype affects skeletal muscle strength in elite athletespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceBursa,Turkeypt_PT
oaire.citation.endPage418pt_PT
oaire.citation.issue8pt_PT
oaire.citation.startPage410pt_PT
oaire.citation.titleJournal of Sports Science and Medicinept_PT
person.familyNameLouro
person.givenNameHugo
person.identifier1741645
person.identifier.ciencia-id8019-E11F-9609
person.identifier.orcid0000-0001-5635-2476
person.identifier.scopus-author-id26425142800
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationf29a2faa-09b7-43c3-b023-0684d0a5d8d3
relation.isAuthorOfPublication.latestForDiscoveryf29a2faa-09b7-43c3-b023-0684d0a5d8d3

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