Life Quality Research Centre

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Phase angle cutoff value as a marker of the health status and functional capacity in breast cancer survivors

Publication . Martins, Alexandre; Oliveira, Rafael; Brito, João; Costa, Tiago; Ramalho, Fatima; Pimenta, Nuno; Santos-Rocha, RA

Accurate predictive tools are key factors for cancer care. Phase angle (PhA) has been proposed as a marker of cellular health, particularly of cell-membrane integrity. Cutoff values have been proposed, including for cancer survivors. This study aimed to assess the usefulness of the proposed PhA cutoff, as a marker of bioelectrical impedance analysis (BIA) assessed health-status, and functional capacity in breast cancer (BC) survivors. This cross-sectional study included 25 women (50.6 ± 8.6 yrs) survivors of BC, divided into two groups according to the PhA reference value of 5.6◦ (group 1 [G1]: PhA ≤ 5.6◦ [n=13]; group 2 [G2]: PhA > 5.6◦ [n=12]) (Gupta et al. 2008). BIA-assessed health status parameters included: extracellular water (ECW), intracellular water (ICW), total body water (TBW), PhA, body mass, fat-free mass, muscle mass, body cell mass (BCM). Four functional tests were performed: 30 s chair-stand test, timed up and go test, ball throw test and 6-minute walking test. Results showed G2 had lower ECW/ICW ratio (p=0.001; ES=1.2), ECW/BCM ratio (p=0.001; ES=3.2) and ECW/TBW ratio (p=0.001; ES=4.8). There was no difference in functional capacity between groups. The results of the present study show that patients with higher PhA values have a higher ICW values and preservation in the ECW/ICW ratio, suggesting it’s a better cell membrane quality and integrity. Relation of both PhA and cell membrane integrity with functional capacity warrants further research.

2021-03-22Journal article

Open access

Learning to cycle: body composition and balance challenges in balance bikes versus training wheels

Publication . Mercê, Cristiana; Cordovil de Matos, Rita; Mafalda Bernardino; dos Santos Bernardino, Mafalda Filipa; Branco, Marco; Catela, David

Abstract: Background/Objectives: Empowering our children and youth to cycle empowers them to pursue a healthier, fuller, and more responsible life. The present study implemented the Learning to Cycle program with the following aims: (i) to promote learning to cycle; (ii) to investigate and compare the use of different learning bicycles, i.e., balance bicycle (BB) and bicycle with training wheels (BTW); (iii) to investigate the influence of body composition during this learning process. Methods: The program was implemented through a quasi-experimental study involving two intervention groups, with pre- and post-test evaluations. The program was applied to 50 children (M = 5.82 ± 0.94 years, 23 girls) who did not know how to cycle previously. One group explored the BB and the other the BTW for six sessions, followed by four more sessions with the conventional bicycle (CB) for both groups. The assessment of independent cycling was considered as the ability to perform, sequentially and unaided, and the various cycling milestones: self-launch, ride, and brake. The children’s body composition was accessed by the BMI’s percentile and classification according to their age and sex. Results: The program had a success rate of 88.24% for acquiring independent cycling, with 100% success in the BB group and 76.92% in the BTW group. The BB children learned significantly faster to selflaunch, ride, brake, and cycle independently. Children with higher BMI percentiles faced greater challenges in achieving balance milestones. Conclusions: BB are recommended, especially for overweight and obese children, as they help develop balance from the onset, and showed to be more efficient in learning to cycle than the BTW.

2025-01-31Research article

Open access