Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.15/453
Título: Phytochemical profile and anticholinesterase and antimicobial activities of supercritical versus conventional extracts of Satureja montana
Autor: Silva, Filipa
Martins, A.
Salta, J.
Neng, N. R.
Nogueira, J.
Mira, Delfina
Gaspar, Natália
Justino, Jorge
Grosso, C.
Urieta, J. S.
Palavra, A. M. S.
Rauter, A. P.
Palavras-chave: Satureja montana
Supercritical fluid extraction
HPLC-DAD
Anticholinesterase activity
Alzheimer's disease
antimicrobial activity
Planta medicinal
Extracto
Doença dos sistema nervoso
Data: 2009
Editora: American Chemical Society
Citação: SILVA, F V. M. 1, MARTINS, A.; SALTA, J.; NENG, N. R.; NOGUEIRA, J. , MIRA, D. 1, GASPAR, N. 1; JUSTINO, J. 1; GROSSO, C., URIETA, J. S.; PALAVRA, A.M.S.; RAUTER, A. P. (2009) - Phytochemical profile and anticholinesterase and antimicobial activities of supercritical versus conventional extracts of Satureja montana. J. Agric. Food Chem., 57 (24): 11557–11563. DOI: 10.1021/jf901786p
Resumo: Winter savory Satureja montana is a medicinal herb used in traditional gastronomy for seasoning meats and salads. This study reports a comparison between conventional (hydrodistillation, HID, and Soxhlet extraction, SE) and alternative (supercritical fluid extraction, SFE) extraction methods to assess the best option to obtain bioactive compounds. Two different types of extracts were tested, the volatile (SFE-90 bar, second separator vs HID) and the nonvolatile fractions (SFE-250 bar, first and second separator vs SE). The inhibitory activity over acetyl- and butyrylcholinesterase by S. montana extracts was assessed as a potential indicator for the control of Alzheimer's disease. The supercritical nonvolatile fractions, which showed the highest content of (+)-catechin, chlorogenic, vanillic, and protocatechuic acids, also inhibited selectively and significantly butyrylcholinesterase, whereas the nonvolatile conventional extract did not affect this enzyme. Microbial susceptibility tests revealed the great potential of S. montana volatile supercritical fluid extract for the growth control and inactivation of Bacillus subtilis and Bacillus cereus, showing some activity against Botrytis spp. and Pyricularia oryzae. Although some studies were carried out on S. montana, the phytochemical analysis together with the biological properties, namely, the anticholinesterase and antimicrobial activities of the plant nonvolatile and volatile supercritical fluid extracts, are described herein for the first time.
Peer review: yes
URI: http://hdl.handle.net/10400.15/453
ISSN: 0021-8561
Versão do Editor: http://pubs.acs.org/doi/pdf/10.1021/jf901786p
Aparece nas colecções:Artigos em revistas internacionais_ESAS

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